Quick answer
What is Setmelanotide?
Built from index records dated 2026-10-09 to 2026-10-13 Compiled by an automated pipeline, checked by The Peptide Observer editorial desk. No qualified clinical reviewer. How this site works
Setmelanotide is a peptide, grouped on this site under Melanocortin receptor peptides, and the 12 research records kept here are 1 from a study in rats or mice, 5 from trials in people and 6 that do not state what kind of study it is.
The literature search returned 220 records. This site keeps 12 of them, which is 5.5 per cent of what came back.
What it is
This site puts it in the Melanocortin receptor peptides group.
A melanocortin-4 receptor agonist, with the active receptor-Gs complex structure reported in the retrieved 2021 record.[1, 2]
Stated in the titles of the cited 2021 Cell Research and 2017 Molecular Metabolism papers.
What kind of records
Several of the records kept here are trials in people.
That sentence is produced by counting, not by reading. What was counted: 5 of 12 indexed records are interventional human trials by their own assigned publication type.
What this does not settle
- What it does in a body. Counting records is not reading them, and nothing here has been read in full.
- Whether it causes harm. No adverse-effect row was taken from any source for this entry.
- How long it lasts. No pharmacokinetics source was retrieved for this entry.
- What the other 208 retrieved records say. They are not in this index.
The longer explanation
Where this comes from
The records cited above, in full.
- Structures of active melanocortin-4 receptor-Gs-protein complexes with NDP-α-MSH and setmelanotide. Cell research (2021). pmid:34561620
- Evaluation of a melanocortin-4 receptor (MC4R) agonist (Setmelanotide) in MC4R deficiency. Molecular metabolism (2017). pmid:29031731