Quick answer
What is IGF-1 DES?
Built from index records dated 2026-10-09 to 2026-10-13 Compiled by an automated pipeline, checked by The Peptide Observer editorial desk How this site works
IGF-1 DES is not a peptide, grouped on this site under Growth factors and growth hormone-derived compounds, and the 12 research records kept here are 7 from studies in rats or mice and 5 that do not state what kind of study it is.
The literature search returned 179 records. This site keeps 12 of them, which is 6.7 per cent of what came back.
What it is
IGF-1 DES is indexed here despite not being a peptide, because the same research literature and the same searches cover it. This site puts it in the Growth factors and growth hormone-derived compounds group.
A truncated insulin-like growth factor I whose activity, per the retrieved records, is not inhibited by IGF-binding proteins; downstream signalling through Akt-1 and p70 S6K is reported in mouse muscle.[1, 2]
Stated in the titles of the cited 1989 Biochemical Journal and 2003 Mechanisms of Ageing and Development papers.
What kind of records
No public chemistry record was found under this name, so the entry describes a preparation, a protein or a mixture rather than one defined molecule.
That sentence is produced by counting, not by reading. What was counted: PubChem returned no compound record for this name, so the subject is a preparation, protein or mixture rather than a defined small molecule; identity fields are unsourced.
What this does not settle
- What it does in a body. Counting records is not reading them, and nothing here has been read in full.
- Whether it causes harm. No adverse-effect row was taken from any source for this entry.
- How long it lasts. No pharmacokinetics source was retrieved for this entry.
- What the other 167 retrieved records say. They are not in this index.
The longer explanation
Where this comes from
The records cited above, in full.
- Insulin-like growth factor (IGF)-binding proteins inhibit the biological activities of IGF-1 and IGF-2 but not des-(1-3)-IGF-1. The Biochemical journal (1989). pmid:2539101
- Age-related differences in the des IGF-I-mediated activation of Akt-1 and p70 S6K in mouse skeletal muscle. Mechanisms of ageing and development (2003). pmid:12875741