Quick answer
What is Humanin?
Built from index records dated 2026-10-09 to 2026-10-13 Compiled by an automated pipeline, checked by The Peptide Observer editorial desk. No qualified clinical reviewer. How this site works
Humanin is a peptide, grouped on this site under Mitochondrial and longevity-associated peptides, and the 12 research records kept here are 6 from studies in rats or mice, 1 from a trial in people and 5 that do not state what kind of study it is.
The literature search returned 587 records. This site keeps 12 of them, which is 2.0 per cent of what came back.
What it is
This site puts it in the Mitochondrial and longevity-associated peptides group.
A mitochondrial-derived peptide; the retrieved records report suppression of apoptosis through interference with Bax activation and an interaction with insulin-like growth factor binding protein.[1, 2]
Stated in the titles of the cited 2003 Nature and 2003 Proceedings of the National Academy of Sciences papers.
What kind of records
A small number of the records kept here are trials in people.
That sentence is produced by counting, not by reading. What was counted: 1 interventional human trial record among 12 indexed records.
What this does not settle
- What it does in a body. Counting records is not reading them, and nothing here has been read in full.
- Whether it causes harm. No adverse-effect row was taken from any source for this entry.
- How long it lasts. No pharmacokinetics source was retrieved for this entry.
- What the other 575 retrieved records say. They are not in this index.
The longer explanation
Where this comes from
The records cited above, in full.
- Humanin peptide suppresses apoptosis by interfering with Bax activation. Nature (2003). pmid:12732850
- Interaction between the Alzheimer's survival peptide humanin and insulin-like growth factor-binding protein 3 regulates cell survival and apoptosis. Proceedings of the National Academy of Sciences of the United States of America (2003). pmid:14561895