The Peptide Observer

Peptide research, explained for people who are not scientists.

Quick answer

What is ACE-031?

Built from index records dated 2026-10-09 to 2026-10-13 Compiled by an automated pipeline, checked by The Peptide Observer editorial desk. No qualified clinical reviewer. How this site works

ACE-031 is not a peptide, grouped on this site under Growth factors and growth hormone-derived compounds, and the 11 research records kept here are 6 from studies in rats or mice, 2 from trials in people and 3 that do not state what kind of study it is.

The literature search returned 12 records. This site keeps 11 of them, which is 92 per cent of what came back.

What it is

ACE-031 is indexed here despite not being a peptide, because the same research literature and the same searches cover it. This site puts it in the Growth factors and growth hormone-derived compounds group.

A soluble activin type IIB receptor described in the retrieved records as a myostatin inhibitor.[1, 2]

Stated in the titles of the cited 2017 Muscle and Nerve and 2026 PLoS One papers.

What kind of records

No public chemistry record was found under this name, so the entry describes a preparation, a protein or a mixture rather than one defined molecule.

That sentence is produced by counting, not by reading. What was counted: PubChem returned no compound record for this name, so the subject is a preparation, protein or mixture rather than a defined small molecule; identity fields are unsourced.

What this does not settle

Where this comes from

The records cited above, in full.

  1. Myostatin inhibitor ACE-031 treatment of ambulatory boys with Duchenne muscular dystrophy: Results of a randomized, placebo-controlled clinical trial. Muscle & nerve (2017). pmid:27462804
  2. ACE-031, a soluble activin type IIB receptor, increases muscle mass and strength in the common marmoset (Callithrix jacchus). PloS one (2026). pmid:41686840